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Track 24: Molecular Pathology

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Call for Abstract/ Research Paper:
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Track 24: Molecular Pathology

Sub Topics: MolecularPathology, GenomicPathology, MolecularDiagnostics, PrecisionMedicine, CancerGenomics, MolecularOncology, PathologyResearch, MolecularBiology, NextGenSequencing, NGS, BiomarkerDiscovery, GeneticTesting, TargetedTherapies, PersonalizedMedicine, TumorGenetics, MolecularProfiling, MolecularMarkers, CancerBiology, MolecularPathologist, PathologyInnovation, ClinicalGenomics, GenomicsResearch, PathologyWorkflow, DigitalPathology, DiagnosticPathology

Molecular Pathology is a specialized field of pathology that focuses on the study and diagnosis of diseases at the molecular level, primarily through the analysis of DNA, RNA, and proteins. It combines techniques from molecular biology with clinical diagnostics to understand how molecular changes, such as genetic mutations or abnormal gene expression, lead to disease development.

Key Aspects of Molecular Pathology:

Genetic Mutations: Identifying changes in the genetic material that can lead to diseases, such as cancer or inherited disorders.

Molecular Diagnostics: Using advanced techniques to detect and analyze molecular markers, guiding diagnosis, treatment, and prognosis.

Precision Medicine: Tailoring treatments based on a patient’s molecular profile, especially in oncology, where targeted therapies can be used for specific mutations.

Biomarker Discovery: Finding molecular indicators (e.g., proteins, genes) that can be used to diagnose or monitor the progression of diseases.

Techniques Used:

PCR (Polymerase Chain Reaction): Amplifies small amounts of DNA or RNA to detect specific genetic sequences.

Next-Generation Sequencing (NGS): A high-throughput technology used to sequence large sections of DNA, helping identify mutations and genetic variations.

FISH (Fluorescence In Situ Hybridization): A technique that detects specific DNA or RNA sequences in cells.

Immunohistochemistry (IHC): Uses antibodies to detect proteins in tissues, often used to confirm molecular diagnoses.

Applications:

Oncology: Identifying mutations in cancer cells to guide targeted therapy.

Infectious Diseases: Detecting pathogens at the molecular level.

Inherited Disorders: Diagnosing genetic conditions based on molecular analysis.

Molecular Pathology is crucial in advancing personalized medicine by allowing healthcare providers to make more precise diagnoses and offer targeted treatments based on an individual's unique molecular makeup.